Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition.
Cesarean birth rates are rising.Uterine dysfunction, the exact mechanism of which is unknown, is a common indication for Cesarean delivery.Biglycan and decorin are two small leucine-rich proteoglycans expressed in the extracellular matrix of reproductive tissues and muscle.Mice deficient in biglycan display a mild muscular dystrophy, and, along wit